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The narcotic antagonists, naloxone or nalmefene, are distinct antidotes for opioid overdose. Opioid antagonists should not be administered in the absence of clinically substantial respiratory or circulatory depression secondary to ROXICODONE (oxycodone hydrochloride) ® overdose. If wanted the appropriate dose of naloxone hydrochloride or nalmefene
Though significant, existence-threatening, or deadly respiratory melancholy can come about at any time during the use of ROXICODONE, the chance is best throughout the initiation of therapy or next a dosage raise.Cureus presents an equitable, productive publishing and peer examining expertise with out sacrificing publication situations.The subsequen